Recent findings at the University of Finland and UVA School of Medicine have overturned 300 years of accepted anatomical fact. Until recent years, the scientific community believed that the lymphatic system — which functions in the body to remove waste and toxins — did not extend into the human brain.
Then came Kari Alitalo. Kari desired a better map of the lymphatic vessels, so three years ago he dosed the lymph cells of mice with a glowing jellyfish gene. At the end of the experiment, he was shocked to see that the mice’s heads were glowing. To be certain his results were correct, he repeated the experiment. His repeat showed exactly the same phenomenon.
As it turns out, Kari had discovered what he termed to be the glymphatic system — the division of the lymphatic system that exists as “glia” cells in the brain.
The Glymphatic System
As it turns out, the glymphatic system may have major implications for degenerative diseases. It’s possible that Alzheimer’s, Huntington’s, and Parkinson’s diseases could be effected by dysfunction in the glymphatic system. A dysfunctional lymphatic system can lead to a buildup of toxins and waste in the body — and a dysfunctional glymphatic system may lead to a buildup of toxins in the brain.
Early studies at Yale and Oregon Health & Science University suggest that a functioning glymphatic system is essential to a healthy brain. Harvard has shown that glymphatic flow is decreased right before a migraine. Research has also shown that the glymphatic system works best when we are asleep, and that sleeping on your side is better than sleeping on your stomach or back.
It’s clear that this revolutionary anatomical discovery will have major impact for clinical therapies for all kinds of neurodegenerative diseases. Read the full article from the Washington Post here, and make sure to subscribe to our blog for the latest news and events across the biotech world.
Alzheimer’s PET Scan – US National Institute on Aging, Alzheimer’s Disease Education and Referral Center
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MA Life Sciences Industry Sees Record Jobs Growth
Biopharma and biopharma manufacturing employment growth across the state outpacing other leading clusters and national averages
CAMBRIDGE, MA (September 2, 2015) – Massachusetts biopharma employment grew by 4.9% in 2014, the highest annual growth rate for the Massachusetts industry since 2008, according to an annual industry report published by MassBio.
The 2015 MassBio Industry Snapshot shows that employment in the biopharma industry rose to 60,459 in 2014, approximately 2,800 jobs more than 2013, based on data from the U.S. Bureau of Labor Statistics’ Quarterly Census of Employment and Wages (QCEW).
Massachusetts also continues to far outpace the nation in biopharma manufacturing employment growth. In the last 10 years, Massachusetts biopharma manufacturing employment has grown by 28.4% to 9,989 jobs statewide. In the same time period, the United States lost 6,329 biopharma manufacturing jobs, a 2.2% decrease.
Link to full story on BioSpace