Drugs in dirt: Scientists appeal for help

US scientists are asking the public to join them in their quest to mine the Earth’s soil for compounds that could be turned into vital new drugs.

Spurred on by the recent discovery of a potential new antibiotic in soil, the Rockefeller University team want to check dirt from every country in the world.

They have already begun analysing samples from beaches, forests and deserts across five continents.

But they need help getting samples.

Which is where we all come in.

Citizen science

On their Drugs From Dirt website, they say: “The world is a big place and we can’t get get to all of the various corners of it.

“We would like some assistance in sampling soil from around the world. If this sounds interesting to you – sign up.”

They want to hear from people from all countries and are particularly keen to receive samples from unique, unexplored environments such as caves, islands, and hot springs.

Such places, they say, could house the holy grail – compounds produced by soil bacteria that are entirely new to science.

Researcher Dr Sean Brady told the BBC: “We are not after hundreds of thousands of samples. What we really want is a couple of thousand from some really unique places that could contain some really interesting stuff. So it’s not really your garden soil we are after, although that will have plenty of bacteria in it too.”

 

Full Story

Where are the new low-cost cancer drugs?

Do common drugs from the pharmacy represent the future of cancer treatment? The Repurposing Drugs in Oncology (ReDO) project, an international collaboration between AntiCancer Fund, Belgium, and US based GlobalCures, finds that existing and widely-used non-cancer drugs may represent a relatively untapped source of novel therapies for cancer.

Currently the main focus in new drug development is on targeted therapies aimed at specific cancer pathways. In spite of major advances, the side-effects and modest effectiveness of such therapies raise concerns; additionally the high cost of these new therapies puts them out of reach for many patients. In contrast, there is strong evidence that some common inexpensive drugs used in the treatment of other diseases (e.g. diabeteshigh blood pressure), have anti-cancer effects that can be exploited in combination treatments.

MNT