Researchers show porous silicon nanoparticles could be harmless to diagnose and treat cancer

The Lomonosov Moscow State University researchers in collaboration with their German colleagues have succeeded in proving that silicon nanoparticles can be applied to diagnose and cure cancer. For the first time the ability of particles to penetrate into the diseased cells effectively and dissolve completely after delivering the drug was shown. The details of the research are presented in the article published in the latest issue ofNanomedicine: Nanotechnology, Biology and Medicine. http://dx.doi.org/10.1016/j.nano.2016.04.004

The scientific direction of the team is called theranostics. This term means a combined ‘therapy’ and ‘diagnostics’, denoting the process of simultaneous detection and treatment of the disease. One of its applications is spotting a range of oncologic diseases with the help of nanoparticles filled with medicine for their targeted delivery into a cancer cell. Nowadays a lot of such nanoparticles do not meet the requirement of biocompatibility. According to one of the researchers, Liubov Osminkina (senior research fellow, Physics Department of Lomonosov Moscow State University), some of the nanoparticles can act quickly, deliver the drug accurately, cure a number of diseases, but months later a patient may suffer from liver, kidney, lung pains, or even headache.

 

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