nivolumab

Cancer drug combination ‘shrinks 60% of melanomas’

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A pair of cancer drugs can shrink tumours in nearly 60% of people with advanced melanoma, a new trial has suggested.

An international trial on 945 patients found treatment with ipilimumab and nivolumab stopped the cancer advancing for nearly a year in 58% of cases.

UK doctors presented the data at the American Society of Clinical Oncology.

Cancer Research UK said the drugs deliver a “powerful punch” against one of the most aggressive forms of cancer.

Melanoma, the most serious form of skin cancer, is the sixth most common cancer in the UK – it kills more than 2,000 people in Britain each year.

 

 

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The results of two international trials against advanced skin cancer have been hailed as “exciting and striking”

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The results of two international trials against advanced skin cancer have been hailed as “exciting and striking”.

Both treatments, for advanced melanoma, are designed to enable the immune system to recognise and target tumours.

The findings were released at the American Society of Clinical Oncology conference in Chicago.

The experimental drugs, pembrolizumab and nivolumab, block the biological pathway cancers use to disguise themselves from the immune system.

Advanced melanoma – skin cancer which has spread to other organs – has proved very hard to treat.

Until a few years ago average survival was around six months.

 

Full Story: BBC